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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NUP214 All Species: 4.55
Human Site: S521 Identified Species: 11.11
UniProt: P35658 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P35658 NP_005076.3 2090 213620 S521 G P G P S T F S F V P P S K A
Chimpanzee Pan troglodytes XP_001166820 2121 216999 S562 G P G P S T F S F V P P S K A
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_850680 1239 128658
Cat Felis silvestris
Mouse Mus musculus Q80U93 2085 212960 A521 G T S T F S F A P P S K G S L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506900 1777 179054 F263 S V N L S E K F A A V E A S T
Chicken Gallus gallus XP_425333 1458 152874
Frog Xenopus laevis NP_001079666 2037 208914 P520 A A G S L Q P P S L P A F S F
Zebra Danio Brachydanio rerio XP_002662271 1013 102782
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W1X4 1711 175157 L197 P K G K Q I V L G F P G G T V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_794482 3338 354012 A1770 G F Q F K L P A S T T S S A P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.6 N.A. 51.8 N.A. 77.8 N.A. N.A. 53.7 51.9 49.9 26.8 N.A. 25.6 N.A. N.A. 20.6
Protein Similarity: 100 97.7 N.A. 53.6 N.A. 84.6 N.A. N.A. 62.6 58.9 65.7 34.5 N.A. 41.4 N.A. N.A. 33.3
P-Site Identity: 100 100 N.A. 0 N.A. 13.3 N.A. N.A. 6.6 0 13.3 0 N.A. 13.3 N.A. N.A. 13.3
P-Site Similarity: 100 100 N.A. 0 N.A. 26.6 N.A. N.A. 13.3 0 20 0 N.A. 13.3 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 0 0 0 0 0 20 10 10 0 10 10 10 20 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 10 0 0 0 0 0 10 0 0 0 % E
% Phe: 0 10 0 10 10 0 30 10 20 10 0 0 10 0 10 % F
% Gly: 40 0 40 0 0 0 0 0 10 0 0 10 20 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 10 0 10 10 0 10 0 0 0 0 10 0 20 0 % K
% Leu: 0 0 0 10 10 10 0 10 0 10 0 0 0 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 10 20 0 20 0 0 20 10 10 10 40 20 0 0 10 % P
% Gln: 0 0 10 0 10 10 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 10 0 10 10 30 10 0 20 20 0 10 10 30 30 0 % S
% Thr: 0 10 0 10 0 20 0 0 0 10 10 0 0 10 10 % T
% Val: 0 10 0 0 0 0 10 0 0 20 10 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _